ncRNA name | rno-miR-200b |
ncRNA Category | miRNA |
Disease name | diabetic retinopathy (DR) |
Species | Rattus norvegicus |
Tissues/Cell_line | retinas |
Methods | luciferase reporter assay, qRT-PCR, Western blot, ADPase histochemical staining, immunohistochemistry |
Expression pattern | down-regulated |
Functional description | In comparison with the control group, the case group showed lower expression of miR-200b but higher expression of VEGFA mRNA. miR-200b might alleviate DR development by down-regulating its target gene VEGFA. |
PubMed ID | 28122882 |
Year | 2017 |
Title | Effects of miRNA-200b on the development of diabetic retinopathy by targeting VEGFA gene. |
Drug-related ncRNA | NO |
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